Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Octenidine dihydrochloride 是一种防腐化合物,可用于皮肤粘膜和伤口。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
100 mg | ¥ 261 | 现货 | ||
200 mg | ¥ 417 | 现货 |
产品描述 | Octenidine is an antibiosis. |
体外活性 | Octenidine concentrations of less than1.5 μM (0.94 μg/mL) causes a greater than 99% reduction of tested microbial population within 15 min. Staphylococcus epidermidis is the most susceptible of the test organisms while E. coli and C. Albicans are the least susceptible[1]. |
体内活性 | The antimicrobial activity of octenidine hydrochloride (OCT) is maintained when applied to the skin of the hands and feet of cynomolgus monkeys. Aqueous octenidine reduces resident microflora populations from 90 to 99.98% at a concentration of 0.2 to 1.6%[1]. A significant reduction in plaque score is observed on the buccal tooth surfaces after daily topical application of 1% solutions of octenidine and chlorhexidine for 7 d; octenidine is more effective than chlorhexidine[2]. |
激酶实验 | The bactericidal activities of OCT and CHG against Staphylococcus aureus are measured by exposing cultures to several different concentrations of each compound for various lengths of time. OCT is diluted from the 5 mM stock solution and tested in phosphate buffer at levels ranging from 0.5 to 5.0 FsM. The test is begun by adding the bacterial culture to the test solution containing OCT or CHG; samples are taken at 5, 15, 30, and 60 min afterward. The inoculum size is approximately 106 CFU/mL[1]. |
别名 | 奥替尼啶, 奥替尼啶双盐酸盐 |
分子量 | 623.82 |
分子式 | C36H64Cl2N4 |
CAS No. | 70775-75-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 6.24 mg/mL (10 mM), Sonication is recommended.
H2O: < 1 mg/mL (insoluble or slightly soluble)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 1.603 mL | 8.0151 mL | 16.0303 mL | 40.0757 mL |
5 mM | 0.3206 mL | 1.603 mL | 3.2061 mL | 8.0151 mL | |
10 mM | 0.1603 mL | 0.8015 mL | 1.603 mL | 4.0076 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Octenidine Dihydrochloride 70775-75-6 Microbiology/Virology Antibacterial Antibiotic inhibit Bacterial 奥替尼啶 Octenidine Inhibitor 奥替尼啶双盐酸盐 inhibitor